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Why is Carbamazepine prescribed?

Tegretol is used in combination or alone with other drugs to treat a few types of seizures in people with epilepsy. This medication is also used to treat trigeminal neuralgia (a disease that causes facial nerve pain). Carbamazepine Equetro brand in extended-release capsules are used to treat episodes of mania (abnormally excited or irritated mood, frenzied) and mixed episodes (mania and depression symptoms that happen at the same time) in people with bipola disorder type I (manic depressive disorder; a disease that causes episodes of mania, episodes of depression, and other abnormal moods). Class of medications: anticonvulsants. Carbamazepine works by reducing abnormal excitement in the brain.

How should Tegretol be used?

Carbamazepine comes as a chewable tablet, oral tablet, an long-acting extended-release (ER) tablet and capsule, and a oral suspension. The tablets and liquid are taken 2 to 4 times a day with meals. The ER tablet is taken twice a day with meals. The ER capsule is taken twice a day with or without meals. You should take it at around the same times every day. Follow the instructions on your prescription label carefully, and ask your pharmacist or doctor to explain any part you do not understand. Take this medication exactly as directed. Do not take more or less of carbamazepine or take it more often than prescribed by your healthcare professional.

Swallow the ER tablets whole; do not split, crush or chew them. The ER capsules may be opened and the beads inside sprinkled over food. Do not chew or crush the ER capsules or the beads inside them.

Shake the suspension well before each use to mix the medicine evenly.

Your doctor will start you on a low dose of this medication and gradually increase your dose.

It may take a few weeks before you feel the full benefit of Tegretol. Continue to take the drug even if you feel well. Do not stop taking Tegretol without talking to your healthcare specialist. If you have a seizure disorder and you suddenly stop taking Tegretol, your seizures may become worse. Your physician will probably decrease your dose gradually.

Carbamazepine other uses

This medication is also sometimes used to treat depression, mental illnesses, posttraumatic stress disorder, restless legs syndrome, drug and alcohol withdrawal, certain pain syndromes, diabetes insipidus, and chorea. Talk to your physician about the possible risks of using carbamazepine for your condition.

Tegretol may be prescribed for other uses; ask your pharmacist or doctor for more information.

Special precautions

Before taking this medicine,

  • tell your healthcare specialist if you are allergic to carbamazepine containing medications, clomipramine (Anafranil), amitriptyline (Elavil), amoxapine (Asendin), nortriptyline (Pamelor, Aventyl), imipramine (Tofranil), desipramine (Norpramin), doxepin (Sinequan, Adapin), other drugs for seizures: trimipramine (Surmontil), phenytoin (Dilantin), phenobarbital (Solfoton, Luminal), protriptyline (Vivactil), or any other medicines.
  • carbamazepine is the active ingredient in several medications that have different trade names and may be prescribed to treat different diseases. Check the list of brand names at online pharmaceutical resources and databases. All of that drugs contain carbamazepine and you should not take more than one of them at the same time.
  • tell your pharmacist or doctor what other prescription and OTC drugs, nutritional supplements, herbal products, vitamins you are taking. Especially mention any of the following: acetazolamide (Diamox); acetaminophen (Tylenol); anticoagulants as warfarin (Coumadin); alprazolam (Xanax); ketoconazole (Nizoral) and itraconazole (Sporanox); cimetidine (Tagamet); clarithromycin (Biaxin); cisplatin (Platinol); clozapine (Clozaril); clonazepam (Klonopin); cyclosporine (Sandimmune, Neoral); daltopristin and quinupristin (Synercid); antidepressants as buproprion (Zyban, Wellbutrin), amitriptyline (Elavil), citalopram (Celexa), buspirone (BuSpar), clomipramine (Anafranil), fluoxetine (Sarafem, Prozac), desipramine (Norpramin), mirtazapine (Remeron), fluvoxamine (Luvox), nortriptyline (Pamelor); danazol (Danocrine); diltiazem (Dilacor, Cardizem, Tiazac); delviradine (Rescriptor); doxorubicin (Rubex, Adriamycin); doxycycline (Vibramycin); haloperidol (Haldol); erythromycin (E-Mycin, E.E.S., Erythrocin); felodipine (Plendil); HIV protease inhibitors atazanavir (Reyataz), indinavir (Crixivan), lopinavir (Kaletra), ritonavir (Norvir, Kaletra), nelfinavir (Viracept), saquinavir (Invirase, Fortovase); levothyroxine (Synthroid, Levoxyl); isoniazid (INH, Nydrazid); lithium (Lithobid); lorazepam (Ativan); loratadine (Claritin); medications to treat malaria: mefloquine (Lariam) and chloroquine (Aralen); drugs for mental illness or anxiety; other medicines for seizures: lamotrigine (Lamictal), ethosuximide (Zarontin), felbamate (Felbatol), oxcarbazepine (Trileptal), methsuximide (Celontin), phenobarbital (Solfoton, Luminal), phenytoin (Dilantin), phensuximide (Milontin), primidone (Mysoline), topiramate (Topamax), tiagabine (Gabitril), valproic acid (Depakote, Depakene); nefazodone; niacinamide (Vitamin B3, nicotinamide); methadone (Dolophine); propoxyphene (Darvon); quinine; praziquantel (Biltricide); rifampin (Rimactane, Rifadin); sleeping pills; sedatives; terfenadine (Seldane) (not available in the United States); theophylline (Theobid, Theo-Dur); tramadol (Ultram); tranquilizers; verapamil (Covera, Calan, Verelan, Isoptin); zileuton (Zyflo); troleandomycin (TAO). Many other drugs may also interact with carbamazepine medications, so be sure to tell your doctor about all the preparations you are taking. Your physician may need to change the doses of your medicines or monitor you carefully for side and other effects.
  • do not take Tegretol if you are taking MAO - monoamine oxidase inhibitors such as phenelzine (Nardil), isocarboxazid (Marplan), tranylcypromine (Parnate), selegiline (Eldepryl); or have stopped taking them within the past two weeks.
  • if you are taking any other liquid medical preparations, do not take them at the same time as carbamazepine suspension.
  • tell your healthcare professional what herbal products you are taking, especially St. John's Wort.
  • carbamazepine medications may decrease the effectiveness of hormonal contraceptives (birth control patches, pills, injections, rings, intrauterine devices, or implants). Use another form of birth control while taking Tegretol. Tell your healthcare professional if think you may be pregnant or if you have unexpected vaginal bleeding while you are usung this medication.
  • tell your physician if you have or have ever had psychosis; glaucoma; kidney, heart, liver, or thyroid disease.
  • if you are having any surgery, tell the dentist or doctor that you are using carbamazepine.
  • tell your healthcare specialist if you are breast-feeding, pregnant, or plan to become pregnant before or while taking carbamazepine.
  • Tegretol may make you drowsy. Do not operate machinery or drive a car until you know how this medicine affects you. Alcohol drinks can add to the drowsiness caused by this drug.
  • tell the doctor about drinking grapefruit juice while taking this carbamazepine.

    Missing a dose?

    Take the missed carbamazepine dose as soon as you remember it. But if it is almost time for the next dose, skip the missed carbamazepine dose and continue your regular dosing schedule without taking a double dose of this medication to make up for a missed one.

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    Carbamazepine side effects

    Tegretol may cause side effects. Tell your healthcare professional if any of these symptoms are severe or do not go away:

  • drowsiness
  • upset stomach
  • unsteadiness
  • vomiting
  • dizziness
  • diarrhea
  • anxiety
  • memory problems
  • headache
  • back pain
  • dry mouth
  • heartburn
  • constipation

    Uncommon side effects and symptoms:

  • depression
  • rash
  • confusion
  • loss of contact with reality
  • thinking, planning or trying about killing yourself
  • chest pain
  • yellowing of the skin or eyes
  • vision problems

    This madication may cause other side effects. Call your physician if you have any unusual problems while taking this drug.

    Storage conditions

    Store carbamazepine away from excess heat and moisture, at room temperature. Keep it in the container, tightly closed, and out of reach of children. Throw away any medicines that is outdated or no longer needed. Talk to your doctor or pharmacist about the proper disposal of your medication.

    Overdose / emergency cases

    In case of overdose, call your local poison control center or local emergency services.

    Common symptoms of overdose:

  • restlessness
  • seizures
  • unconsciousness
  • abnormal movements
  • muscle twitching
  • unsteadiness
  • drowsiness
  • dizziness
  • shaking of a part of your body
  • irregular or slowed breathing
  • blurred vision
  • rapid or pounding heartbeat
  • upset stomach
  • vomiting
  • difficulty urinating

    Other information

    Before having any laboratory test, tell the laboratory personnel and your doctor about using carbamazepine.

    Tegretol can interfere with the results of home pregnancy tests. Talk to your physician if you think you might be pregnant while you are taking this medication. Don't try to test for pregnancy at home.

    You may notice the ER tablet coating in the stool because carbamazepine ER tablet does not dissolve in the stomach after swallowing. It slowly releases the medicine as it passes through your digestive system.

    Do not let anyone else take your medicines. Ask your pharmacist or doctor any questions you have about refilling your prescription.


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